The ELIXIR Core Data Resources (CDRs) have been selected based on their quality, wide usage, and long-term significance. They are essential to many fields of research, including genomics, proteomics, and drug development. ELIXIR Core Data Resources provide researchers with open and reliable access to biological datasets, promoting new discoveries and accelerating, for example, the development of new drugs, the understanding of diseases, and the identification of biomarkers.
The data analysis services and machine learning models provided by the ELIXIR infrastructure can help identify new drug candidates from large datasets. These resources and databases allow natural compounds to be analysed more quickly and accurately, supporting their development into safe and effective pharmaceuticals.
These are for example ENA, ChEBI and Ensembl. ENA (European Nucleotide Archive) is a database maintained by the European Bioinformatics Institute (EMBL-EBI) that stores and shares sequencing data from various organisms, including microbes, plants, animals, and humans.
ChEBI (Chemical Entities of Biological Interest) is a curated biochemical database that contains information about biologically relevant small-molecule compounds. Ensembl is a genomics and bioinformatics database that provides analysed genomic data from a range of organisms, including humans, animals, plants, and microbes.
The database can be used to look up the biological effects of compound and its target molecules as well as genetic and protein structure data and related genes, aiding research into drug resistance and the effects of mutations.
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ELIXIR is partly funded by the European Commission